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managing fatigueAccording to the Centers for Disease Control and Prevention, over 15% of women and 10% of men experience fatigue. Fatigue is characterized by a lack of mental or physical energy, low initiative, and increased feelings of tiredness. Mitochondria, organelles found in the body’s cells, are known as the body’s “powerhouses” since they play an important role in energy production. Managing fatigue by supporting your body’s mitochondria and the process of energy production may involve consuming a balanced diet, engaging in regular physical activity, optimizing sleep, managing stress, and taking certain dietary supplements.  Click here for a quick fatigue test.
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The following is for educational purposes only and none of these statements have been evaluated by the FDA. Please consult with your health practitioner before self-prescribing supplementation to help assist you in choices unique to your health and inform you of any contradictions. Below is some useful information about top recommended supplements for energy support, including popular products from my dispensary. Products are not sold to the general public and are available only to clients of our office.

NADH: Nicotinamide adenine dinucleotide
NADH is the bio-available, anti-oxidant form of Vitamin B-3. Known as the biological rocket fuel, NADH is essential to the production of ATP (cellular energy) and may help with managing fatigue. NADH is also involved in basic metabolism, the breakdown of glucose and fats, and supplies energy to the brain, nerves, muscles, heart and all other organs, in order to function. NADH is also a potent antibiotic, helps DNA repair, boost immune system, and helps cell regeneration.
ENADA MOJO was designed for High Level Performing Athletes and High Demand Executives where high levels of energy, mental clarity and alertness are needed the most. Being a sublingual tablet is provides almost immediate energy. Unfortunately, this product is no longer available via FullScript and is special order from our office (link).

Vibrant (TCM Rx)
This Chinese Medicine Prescription formula is designed for tiredness, fatigue, lack of energy, chronic fatigue syndrome, and as a Sports formula: to increase mental and physical performance. Vibrant increases basal metabolism to increase energy levels and sense of well-being. Vibrant has an adaptogenic function helping the patient adapt to stress, and improve mental and physical functions.
Vibrant Formula by Evergreen Herbs (Special Order Link)

Acetyl-l-carnitine
The amino acid carnitine, found in high amounts in cardiac and skeletal muscle tissue, is involved in transporting long-chain fatty acids into mitochondria to be used for energy. One form of carnitine, acetyl-l-carnitine (ALCAR), may be better absorbed and has been found to cross the blood-brain barrier. Research suggests that ALCAR supplementation may delay the deterioration of mitochondria and reduce mental and physical fatigue associated with aging.
Alpha lipoic acid 
Alpha lipoic acid (ALA), obtained through dietary sources and synthesized in the mitochondria, is an antioxidant and cofactor in mitochondrial energy production and may help with managing fatigue. ALA helps to regenerate other antioxidants, including vitamins C, E, and glutathione, the body’s master antioxidant. As a dietary supplement, the antioxidant and anti-inflammatory effects of ALA may benefit individuals with diabetic neuropathy and central nervous system disorders, such as multiple sclerosis and Parkinson’s disease.
B vitamins
The eight B vitamins are essential to brain function and energy production. Deficiency in one or several of these vitamins, such as pyridoxine (B6) and cobalamin (B12), may result in neurological symptoms and cognitive decline. Additionally, thiamin (B1), riboflavin (B2), niacin (B3), and folate (B9) have been studied for their potential to improve symptoms of mitochondrial disorders. In individuals with these conditions, supplementation may reduce fatigue, improve exercise tolerance, and improve general well-being.
Coenzyme Q10
A fat-soluble compound, coenzyme Q10 (CoQ10) is synthesized in the body, found in certain foods, including fish, meat, and whole grains, and commonly used as a supplement. CoQ10 is an antioxidant and a cofactor in the electron transport chain, a critical cycle that occurs in the mitochondria, which supports cellular energy production. Although research findings are mixed, there is some evidence that CoQ10 supplementation may benefit individuals with mitochondrial disorders by increasing muscle strength and improving energy repletion.
N-acetyl-cysteine
N-acetyl-cysteine (NAC) is a precursor to the amino acid cysteine and the potent antioxidant glutathione. Preliminary research suggests that NAC supplementation may benefit individuals with chronic fatigue syndrome and protect against degenerative processes, including neurodegenerative diseases and myocardial dysfunction. Further, studies in athletes have shown that NAC may increase athletic performance.
To learn more, see the FullScript handouts on Fatigue and Mitochondria.
If you have any issues accessing the dispensary, let us know. We may just need your paperwork updated. Additionally, please use caution when self-prescribing as many supplements are practitioner grade and ingredients may already exist in other supplementation in different forms you may already be taking.
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